Non-Enzymatic Post-Translational Modifications in the Development of Age-Related Macular Degeneration

نویسندگان

  • Yuichi Kaji
  • Tetsuro Oshika
  • Noriko Fujii
چکیده

Age-related macular degeneration (AMD) is a leading cause of blindness among Caucasians in various countries.1-3 In addition, cases of AMD are increasing among non-Caucasians, and AMD has become one of the major causes of blindness worldwide. To address this problem, several etiological, pathological, and basic science studies are being conducted. Etiological studies have revealed that the risk factors of AMD include smoking,4 increasing age, and the presence of cardiovascular disorders.5 However, the molecular mechanisms linking these risk factors to AMD are still unclear.

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تاریخ انتشار 2017